Natural Products: Insights into Leishmaniasis Inflammatory Response
نویسندگان
چکیده
منابع مشابه
Natural Products: Insights into Leishmaniasis Inflammatory Response
Leishmaniasis is a vector-borne disease that affects several populations worldwide, against which there are no vaccines available and the chemotherapy is highly toxic. Depending on the species causing the infection, the disease is characterized by commitment of tissues, including the skin, mucous membranes, and internal organs. Despite the relevance of host inflammatory mediators on parasite bu...
متن کاملInsights into Natural Products in Inflammation
The inflammatory process comprises immune, vascular and cellular biochemical reactions, involving different cells, enzymes, cytokines, eicosanoids and transcription factors. It includes the triggering of signaling cascades, the activation of transcription factors, gene expression, increased levels of inflammatory enzymes, and the release of various oxidants and pro-inflammatory molecules in imm...
متن کاملAnti-Inflammatory Natural Products
1Laboratory of Immunology and Virology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China 2Program in Cellular and Molecular Medicine, Boston Children’s Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA 3Joslin Diabetes Center, Harvard Medical School, Boston, MA 02115, USA 4Division of Infectious Diseases, Cincinnati Children’s Hospit...
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Epidemics of fatal visceral leishmaniasis caused by the intracellular protozoan Leishmania are a severe public health problem in tropical and subtropical regions of the world. One major drawback in the treatment of leishmaniasis is the emergence of resistance to current chemotherapeutics. Leishmanicidals have to be administered in low doses since commonly used drugs exhibit severe side effects,...
متن کاملAnti-Inflammatory Activity of Natural Products.
This article presents highlights of the published literature regarding the anti-inflammatory activities of natural products. Many review articles were published in this regard, however, most of them have presented this important issue from a regional, limited perspective. This paper summarizes the vast range of review and research articles that have reported on the anti-inflammatory effects of ...
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ژورنال
عنوان ژورنال: Mediators of Inflammation
سال: 2015
ISSN: 0962-9351,1466-1861
DOI: 10.1155/2015/835910